VEGFB and neoplasm: While RIP1-Tag2; RIP1-VEGFB mice presented with a similar number of tumors as RIP1-Tag2 mice (Figure 2c, left), expression of the VEGF-B transgene unexpectedly resulted in a significant reduction in total tumor burden by 39% (Figure 2c, right; 59.0±8.2 mm3vs 35.7±4.2 mm3; p<0.05).