VEGFB and neoplasm: However, in agreement with the reduced tumor burden of RIP1-Tag2; RIP1-VEGFB mice, the average tumor volume of RIP1-Tag2; Vegfb−/− mice was increased by 81% compared to RIP1-Tag2; Vegfb+/− (33.6±29.9 mm3vs 18.6±21.3 mm3; Figure 5a, right; p<0.05).