The basal and stimulated t-PA release were comparable (P = 0.69 and P = 0.87, respectively) between migraine patients (-0.6 ± 1.1 ng.dL-1.min-1 and 7.4 ± 5.5 ng.dL-1.min-1) and controls (-0.6 ± 2.1 ng.dL-1.min-1 and 7.1 ± 5.5 ng.dL-1.min-1). The gene discussed is PLAT; the disease is migraine disorder.