After initial patient hesitancy, she (at twenty seven weeks of fetal gestational age) underwent a right breast incisional biopsy (under local anesthesia) with histopathology results showing estrogen receptor positive, progesterone receptor negative and human epidermal growth factor receptor 2 (HER2) positive invasive ductal Carcinoma with grade 3 multifocal Ductal Carcinoma In Situ (DCIS) (Figure 1). This evidence concerns the gene ERBB2 and ductal breast carcinoma in situ.