RhoC-GTPase, Granulin-epithelin precursor (GEP), Vimentin (VIM), and Platelet-derived growth factor receptor alpha (PDGFRA) were identified as being over-expressed in highly metastatic HCC and therefore may be considered for future strategies targeting the metastatic potential of HCC [34-39]. The gene discussed is VIM; the disease is hepatocellular carcinoma.