The second subnetwork consisted of 14 under expressed cancer genes (FBXW7, GABRA1, MYT1L, NEFL, NEFM, SNAP25, SYT1, VSNL1, RTN1, SH3GL2, SV2B, SYN2, KIAA0774 and RIMS2) which were regulated by 10 over expressed miRNAs (mir-15b, mir-25, mir-16, mir-92, mir-15a, mir-320, mir-106b, mir-93, mir-106a, and mir-17-5p) in the mRNA coexpression network. This evidence concerns the gene SV2B and cancer.