We evaluated the average ratio of BRG1-positive cells in normal colorectal mucosa, adenoma and CRC as well as that of BRM-positive cells, and found that the average ratios of BRG1-positive cells in normal colorectal mucosa, adenoma and CRC were 31.9±1.6, 66.5±3.3, and 90.6±1.8%, respectively (P<0.05, Student's t-test, Figure 1B). The gene discussed is SMARCA2; the disease is colorectal carcinoma.