SMARCA4 and neoplasm: In human cancers, aberrant expressions of BRG1 and BRM have been documented in the development of tumours, including those of the stomach (Sentani et al, 2001; Yamamichi et al, 2007), lung (Reisman et al, 2003), prostate (Sun et al, 2007) and melanocytes (Lin et al, 2010); nevertheless, there is a major discrepancy in the biological significance of BRG1.