APOE and retinitis: Similarly, the significantly attenuated rod and rod-cone b-waves (−2.7 log cd.sec.m-2 and 0.6 log cd.sec.m-2, respectively) are also suggestive of inner retinal dysfunction in saline-treated ApoE−/− compared to WT mice (Figure 5A, C); treatment of ApoE−/− mice with EP80317 significantly attenuated the loss of the scotopic rod and rod-cone responses (Figure 5A-C).