CFD/Adipsin median levels were found to be lower in tumours compared to the levels in PN and AN (p = 0.0324), while CXCL5/ENA78, CCL20/MIP-3α, IGFBP3, SPP1/OPN and TIMP1 were increased in PN and tumours relative to AN, with higher levels seen in tumours. Here, SPP1 is linked to neoplasm.