Twenty-two of the 31 sarcoidosis BAL samples produced a CD4+ response to at least one of the mycobacterial epitopes of ESAT-6, KatG, Ag85A, sodA, or HSP, compared to two of 14 PPD- controls (p = 0.00084) and five of nine NTM controls (p = 0.437) (Figure 1A, B; Table 3). This evidence concerns the gene CD4 and sarcoidosis.