When compared to PPD- controls, there was a significant difference in the distribution of the sarcoidosis Th-1 immune response against ESAT-6 (p = 0.004, Wilcoxon), katG (p = 0.06, Wilcoxon), and Ag85A (p = 0.014, Wilcoxon) (Figure 2). The gene discussed is NELFCD; the disease is sarcoidosis.