Collectively, tumor size 1 and 2 showed hypermethylation of DR5 (68%; P = 0.002), DCR1 (63%; P = 0.001) and DCR2 (80%; P = 0.0000001) as well as hypomethylation of DR4 (58%; P = 0.011), FLIP (61%; P = 0.007) and ATM (59%; P = 0.013) after Benjamini Hochberg correction. Here, ATM is linked to neoplasm.