Multivariate Cox regression analysis demonstrated that neither SNAS (HR 1.87, 95% CI 0.71-4.88, p = 0.194) nor CNR (HR 0.41, 95% CI 0.15-1.13, p = 0.087) were independent predictors of BCSS in tamoxifen-treated patients; however, a low CNR was an independent predictor of OS in tamoxifen-treated patients (HR 0.44, 95% CI 0.23-0.87, p = 0.018), after controlling for age, tumour size, nodal status, grade, PR and Her2 status (Table 3). The gene discussed is ERBB2; the disease is neoplasm.