PFKFB2 and acute lymphoblastic leukemia: To elucidate whether GC exclusively regulated PFKFB2 in lymphoid cells, or whether other PFKFB-isoenzymes are susceptible to GC-treatment as well, we re-analyzed this data using the more robust GCRMA normalization and included 18 additional ALL patients undergoing GC therapy as well as 3 non-leukemic children who received GC as part of their epilepsia treatment, and 6 GC-sensitive and 6 GC-resistant derivatives of the CEM-C7H2 T-ALL cell line.