Thus, a combination of traditional and non-traditional risk factors may account for the high prevalence of CVD in SLE including dyslipemia, hypertension, oxLDL, anti-phospholipid antibodies (aPL) and raised activity of inflammatory factors like TNF and PAF-acetylhydrolase (LDL-PLA2), C-reactive protein (CRP) [5,19-22]. This evidence concerns the gene CRP and hypertensive disorder.