Significant difference between control and HCC was also observed in DCP values (P < 0.0001) with median (range) values were 1.5 ng/mL (0.5-12.3 ng/mL), 6.3 ng/mL (0.9-4273.8 ng/mL) and 356.4 ng/mL (0.4-14245 ng/mL), in control, AFP-low and AFP-high, respectively. This evidence concerns the gene AFP and hepatocellular carcinoma.