MEC-1 (a B-CLL derived cell line) showed high expressions of both receptors whilst Nalm6 (pre-B Acute Lymphoblastic Leukemia derived cell line) and Reh (Acute Lymphoblastic Leukemia) cells had a similar level of CRAM but no CCR7 (Figure 1A). This evidence concerns the gene CCR7 and B-cell chronic lymphocytic leukemia.