Nevertheless, the present assay for VEGF-mediated angiogenesis has demonstrated a close correlation between the anti-angiogenic effects in the tumor-free mesentery on one hand and the anti-tumor and indirectly assessed anti-angiogenic effects in the tumors on the other hand after continuous paclitaxel infusion in a rat model of syngeneic prostate cancer (38). The gene discussed is VEGFA; the disease is prostate cancer.