In this report, we investigated the potential of RT-qPCR measurement of BCR-ABL transcript levels to predict cytogenetic relapse by monitoring the BCR-ABL transcript every 4 to 12 weeks throughout imatinib treatment in 91 CP-CML patients who had achieved CCyR and MMR. Here, ABL1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.