ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive: Contrary to the results reported by Palandri et al., Kantarjian et al found that most of the patients with increases in BCR-ABL remain in CCyR and that patients who had CML progression (9.5%) were those who either lost MMR or never had MMR and who had > 1 log increase of BCR-ABL transcript.