Further it was demonstrated that these MFH samples showed frequent co-amplification of either 1p32 or 6q23, which was not observed in the liposarcomas, suggesting that the lack of differentiation may be a consequence of amplification of target genes located in these regions, like the ASK1 (MAP3K5) gene in 6q23 [24], [25]. This evidence concerns the gene MAP3K5 and liposarcoma.