ANG and amyotrophic lateral sclerosis: Using data pooled from the three populations and after correcting for age and sex, angiogenin levels were significantly lower in ALS patients than in controls in plasma/serum (mean ± SD  = 438.2±112.2 ng/ml for the ALS group and 467.6±105.4 ng/ml for controls; p = 0.001, Mann-Whitney-Wilcoxon test) and in CSF (mean ± SD  = 5.582±1.754 ng/ml for the ALS group and 6.197±1.987 ng/ml for controls; p = 0.01, Mann-Whitney-Wilcoxon test).