Likewise, in subjects with and without severe sepsis as well as in subjects with PCT≥0.25, there was an age-related increase in D-dimer (p = 0.02, <0.01, and 0.02, respectively) and no age-related difference in IL-6 (p = 0.86, 0.42, and 0.53, respectively) (Table 4). The gene discussed is IL6; the disease is Sepsis.