MTOR and acute lymphoblastic leukemia: Our results showed that Dex had minimal effects on the cell growth and apoptosis of the GC-resistant T-ALL cell lines, but when it was used to co-treat the cells with rapamycin, a stronger growth inhibitory and apoptosis-inducing effect was achieved and it was done through synergistically inhibiting mTOR signaling, suggesting a rationale of adding mTOR inhibitor in the treatment of GC resistant T-ALLs in clinics.