The observation that the expression of SF2/ASF and Caspase-9a correlates positively in tumorous but not in control samples may possibly suggest that while in non-cancerous kidney tissues the splicing of Caspase-9 is affected by multiple different factors (for instance, by E2F1 and SC35), in cancer tissues SF2/ASF may play the main role. Here, E2F1 is linked to cancer.