BMP7 and nephrosclerosis: As illustrated by double immunofluorescence (Figure 2, 3, 4) and immunohistochemistry (Figure 5), localisation of the BMP-7 expression was unchanged in patients with nephrosclerosis, but the mean intensity was significantly lower (0.86 ± 0.17) compared to controls (2.5 ± 0.07) (95% confidence interval (CI) 0.23 - 3.10, p < 0.05).