The B-cell chronic lymphocytic leukemia (CLL)/lymphoma 11B (BCL11B) gene plays a crucial role in T-cell development, differentiation, and proliferation [7], and altered expression, mutation, disruption, or rearrangement of BCL11B have been associated with T-cell malignancies [8-11]. The gene discussed is BCL11B; the disease is B-cell chronic lymphocytic leukemia.