Relative expression levels of BCL2L1 mRNA (397.82 ± 565.98%) and CREBBP mRNA (53.28 ± 39.21%) in patients with T-ALL were significantly higher than those from healthy controls (BCL2L1: 10.83 ± 11.18%; CREBBP: 20.80 ± 13.50%; P < 0.05), whereas the relative expression levels of TNFSF10 and SPP1 mRNA showed no significant difference between T-ALL and healthy groups (Figure 2F). This evidence concerns the gene CREBBP and acute lymphoblastic leukemia.