The CRC cell line LOVO showed modestly increased levels of SGK1 expression (3.7 to 6.2-fold), while the RIE-1 cell line, which was used as a control as it is derived from normal small intestinal cells of rat origin, showed a prominent increase in Sgk1 levels (average fold change = 21; t-test p-value = 1.2×10−5) as expected from previous reports (Fig. 1a). The gene discussed is SGK1; the disease is colorectal carcinoma.