MYOF and autosomal recessive nonsyndromic hearing loss 9: Ferlin is essential for the fusion of vesicles with the cell membrane.[10] Mutations in otoferlin cause an autosomal recessive form of congenital deafness (DFNB9, MIM #601071).[12] Otoferlin is expressed in hair cells in the inner ear [13], and participates in the trafficking of synaptosomal vesicles.[14] Myoferlin is like dysferlin strongly expressed in muscle.[15] It has been suggested that myoferlin might be able to replace dysferlin as a potential strategy for therapy of dysferlinopathies.[15], [16] The exact function of myoferlin remains unclear.