In data from the hospital case–control study conducted at MD Anderson Center in the United States, Li et al noted significantly reduced overall survival in patients with the OGG1 C315G (rs1052133) GG homozygous variant genotype.32 Furthermore, they reported a weak interaction of the OGG1 C315G CC/CG genotype with diabetes in pancreatic cancer. This evidence concerns the gene OGG1 and familial pancreatic carcinoma.