MX1 and cryohydrocytosis: Having established that a baseline expression of miR-1, miR-30, miR-128, miR-196 and miR-296 could be recorded in PBMCs collected from healthy donors before and after in-vitro IFN alpha treatment, we decided to analyse the expression of the same miRNAs, as well as MxA, in 12 patients with CHC, of whom 7 were classified as responders and five as non-responders to Peg-IFN alpha plus ribavirin therapy.