Glucose, Insulin and Homeostasis Model Assessment for insulin resistance (HOMA-IR) at different time points of male and female wild-type (WT) and transgenic (TG) (HSA-UCP1) mice fed three different semisynthetic macronutrient diets ad libitum from 12 weeks of age (data are shown as mean ± SEM). Here, INS is linked to Insulin resistance.