DMT1, a proton-coupled metal transporter that participates in iron influx to the cell from the extracellular matrix and/or from recycling endosomes [33] has been shown to contribute to the neurodegenerative process occurring in Parkinson disease (PD), where an increase in the expression of DMT1 (+IRE) in the sustancia nigra of patients with PD correlates with an increase in iron content [34]. The gene discussed is SLC11A2; the disease is Parkinson disease.