Univariate survival analysis showed that sex, pathological TNM stage, pathological N stage, histological subtype (adenocarcinoma or not) and TopIIα expression level were prognostic factors related to DFS, while age, smoking history, surgical methods, pathological T stage, chemotherapy regimens and expression level of Ki67 were of no prognostic significance. The gene discussed is TOP2A; the disease is adenocarcinoma.