HLA-DRB1*13 was the most prevalent allele in autoimmune hepatitis patients with positive HAV IgM in this study however HLA-DRB1*12 was the only statistically significant allele in those patients compared to patients with negative hepatitis A IgM and no significant difference as regards other alleles was found (Table 4). The gene discussed is HLA-DRB1; the disease is autoimmune hepatitis.