In addition to the cell-lines, four primary GBM cell cutures, which were derived from patient's tumor samples [16], were analysed for MMP-1, -8, -9, -10, -11, -13, -17, -19, -23, -24 and MMP-28 mRNA expression by semiquantitative RT-PCR (Figure 3). Here, MMP1 is linked to neoplasm.