BCL2 and plasma cell myeloma: Western blotting and further quantification analysis showed that Bik expression was directly correlated to Bcl-2 protein expression in both HMCL (Spearman's ρ=0.639 P=0.0006) (Figure 1C) and primary myeloma cells (Spearman's ρ=0.815 P=0.0005).