Plasma concentrations of vWF, fasting blood glucose, total cholesterol were not significantly different between the two groups (P = 0.15; P = 0.17; P = 0.17), whereas the levels of fasting insulin, HOMAIR, colesterol HDL and PAI-were higher in PCOS patients (P < 0.05). The gene discussed is VWF; the disease is polycystic ovary syndrome.