CYP11A1 and familial pancreatic carcinoma: For example, the thyrotropin-releasing hormone receptor signaling pathway was reported to promote programmed cell death in pancreatic cancer [58]; steroid biosynthesis in pancreatic cancer was found based on analyses of several steroidogenic enzymes, such as the cytochrome P-450scc enzymatic complex (P450scc) that is responsible for the conversion of cholesterol into pregnenolone.