These observations are supported by the results of several genetic association studies that detected preferential associations between a Toll-like receptor 2 (TLR2) polymorphism and tuberculosis meningitis caused by Beijing strains [12], as well as between variants of 5′-lipoxygenase (ALOX5) and pulmonary tuberculosis caused by M. africanum, but not M. tuberculosis[13]. This evidence concerns the gene TLR2 and pulmonary tuberculosis.