INS and rickets: Subsets of people with mild manifestations of the type 1 autoimmune disease process could benefit from treatments aimed at improving the insulin-resistant state.17 There is evidence that vitamin D is important in the prevention of islet cell death.18 Reports have shown the association of hypovitaminosis D with insulin resistance and beta-cell dysfunction,3, 19, 20 and vitamin D is required to improve the production of insulin.3, 4 There are few studies that have examined the effect of supplementation with a variety of formulations of vitamin D on type 2 diabetes mellitus parameters.