CCND2 and astrocytoma (excluding glioblastoma): Six astrocytoma cell lines (U87MG, A172, LN405, SW1783, T98G and SW1783) expressed Cyclin D2 at very low levels, and two cell lines (CCF-STTG-1 and GOS-3) did not express Cyclin D2 compared to normal adult brain tissue (p = 0.006) (Figure 4B).