TLR4 and Alzheimer disease: In AD tissues the TLR-4+ cells rose to 16.8% and 25.4%, respectively (p < 0.05 when compared with percentage of TLR-4+ cells in healthy tissues and UC), while in AC their levels additionally increased up to five times (19.6% and 28.2%, in the epithelial and stromal compartments, respectively; p < 0.05).