To determine the relative roles of CD4 and CD8 T cell subsets in inducing tumor regression, BALB/c mice bearing 4 day tumors and pre-treated with CYP, underwent AIT using untreated B/I activated DLN cells, C'-treated cells, anti-CD4 + C'-treated cells, or anti-CD8 + C'-treated cells. Here, CD8A is linked to neoplasm.