For PAI-1, severity of periodontitis showed a positive correlation (β = 0.356, p = 0.001), but there was no association with IgG against Aa and Pg. Also for D-dimer both female gender and BMI showed positive correlations, while cholesterol showed a negative correlation; IgG against Pg was retained in the final model, with a negative correlation (β = -0.190), but this association did not reach a statistical significance (p = 0.085). Here, SERPINE1 is linked to periodontitis.