GPT and Hepatic fibrosis: There was no significant difference in the serum levels of ALT, lactate dehydrogenase (LDH), total bilirubin (T-bil), total protein (TP), albumin (Alb), and the serum albumin/globulin (A/G) ratio between the wt and Syno+/− mice both in natural conditions and in this liver fibrosis model (Fig. S2 and S3).