In an unadjusted analysis, HLA-B*44:02 is strongly associated with MS in our discovery dataset (OR 0.67, ), however this association is positively confounded by the DRB1*15:01 association (r = ¿0.05), and by the (putative) protective effects of HLA-A*02:01 () and DRB1*04:01 (). This evidence concerns the gene HLA-DRB1 and myeloid sarcoma.