The next article examines the role of glyoxalase I in the inhibition of methylglyoxal advanced glycation end products-AGEs formation in lenses of transgenic mice overexpressing human glyoxalase I, and the fourth one reviews the pathophysiological characteristics of ocular complications in the Spontaneously Diabetic Torii rat such as the formation of cataracts which can become hypermature. Here, GLO1 is linked to cataract.