CXCR4 and familial pancreatic carcinoma: Our data showed an increased level of phospho-BAD in both Panc1 and MiaPaCa cell lines treated with CXCL12 (Figure 4), suggesting that it could be one of the mechanisms by which CXCL12–CXCR4 signalling axis protects the pancreatic cancer cells from apoptosis.