To further confirm that expression of these RGS transcripts is reduced in drug resistant cancer cells, we directly measured expression of RGS transcripts in parental Hey-A8 ovarian cancer cells and taxane-resistant derivatives of this cell line (commonly referred to as Multi-drug resistant or MDR-HeyA8 cells, although they retain cisplatin sensitivity; see Additional file 1). Here, PITX2 is linked to ovarian cancer.