Genes that were significantly up-regulated after Bonferroni correction for multiple testing in both studies included TOP2A, MKI67, CDC2, TPX2, SEC14L1, EIF2C2, THBS2, EZH2, CDKN3, BUB1, PGK1, CCNB1, HPRT1, MSR1, WDR67, CTHRC1, BIRC5, TAF2, YY1, RAD21, RAP2B, FAM49B, SQLE, F2R, CHRAC1, INHBA, SDHC, and NOX4. Significantly down-regulated genes in both studies included PAGE4, SRD5A2, and AZGP1. We hypothesize that these 31 genes may be used to predict tumor progression after surgery. The gene discussed is PAGE4; the disease is neoplasm.