Within the linkage region, the six genes cadherin 6, type II (CDH6), cadherin 10, type II (CDH10), cadherin 12, type II (CDH12), PDZ domain-containing protein 2 (PDZD2), Golgi phosphoprotein 3 (GOLPH3), zinc finger RNA binding protein (ZFR) were selected as candidate genes on the basis of their function: cell adhesion, intracellular signal transduction, protein trafficking, and DNA/RNA binding activities, which we thought were the functions most likely to be associated with myopia. Here, PDZD2 is linked to myopia.