CEACAM5 and neoplasm: According to univariate analysis, age, tumor depth, nodal metastasis, histological grade, TNM stage, CEA mRNA positivity and serum CEA positivity were significantly related to disease-free survival (P = 0.031, <0.001, 0.001, 0.022, <0.001, 0.001, 0.045 respectively) (Table 3).